The cold chain for the conservation of vaccines against covid-19: systemic review

Resumen

The cold chain is a set of standards and procedures that ensure the correct storage and distribution of vaccines to health services from the national to the local level. Objective: To examine the scientific evidence on the cold chain for the conservation of COVID-19 vaccines. Methodology: An organized exploration of original articles was carried out by searching scientific articles published in databases such as: PubMed, SciELO, Web of Science, Google Scholar, also documents from health organizations and authorities; using the following keywords (cold chain, vaccine conservation, knowledge, nursing personnel, Covid-19); with a maximum age of 5 years and without limitation of languages.  Results: According to the information obtained, the recommendations for conservation in transport are expressed by the manufacturer refrigerated (2◦C to 8◦C) storage at the place of administration before diluting or piercing the vial. Storage after diluting or piercing the vial: should be at temperature of 2◦C to 25◦C: stable 6 hours.  Conclusion: Considering the cold chain as a set of norms and procedures that ensure the correct storage and distribution of vaccines, these norms should be followed to keep them in good condition at the time of administration to the patient.